Publications

Preprints

Sreenivasan AP, Vaivade A, Noui Y, Khoonsari PE, Burman J, Spjuth O, Kultima K.
Conformal prediction enables disease course prediction and allows individualized diagnostic uncertainty in multiple sclerosis
medRxiv. 2024.03.01.24303566 (2024). DOI: 10.1101/2024.03.01.24303566

2024

2023

Ye S, Agalave NM, Ma F, D Mahmood DF, Al-Grety A, Khoonsari PE, Svensson CI, Kultima K, Vera PL.
Lumbosacral spinal proteomic changes during PAR4-induced persistent bladder pain
Neurosci Lett. (2023). DOI: 10.1016/j.neulet.2023.137563
Braun M, Boström G, Ingelsson M, Kilander L, Löwenmark M, Nyholm D, Burman J, Niemelä V, Freyhult E, Kultima K, Virhammar J.
Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases
Fluids Barriers CNS. (2023). DOI: 10.1186/s12987-023-00472-x
Vaivade A, Wiberg A, Khoonsari PE, Carlsson H, Herman S, Al-Grety A, Freyhult E, Olsson-Strömberg U, Burman J, Kultima K.
Autologous hematopoietic stem cell transplantation significantly alters circulating ceramides in peripheral blood of relapsing-remitting multiple sclerosis patients
Lipids Health Dis. (2023). DOI: 10.1186/s12944-023-01863-7
Herman S, Arvidsson McShane S, Zjukovskaja C, Khoonsari PE, Svenningsson A, Burman J, Spjuth O, Kultima K.
Disease phenotype prediction in multiple sclerosis
iScience. (2023). DOI: 10.1016/j.isci.2023.106906
Lundblad K, Zjukovskaja C, Larsson A, Cherif H, Kultima K, Burman J.
CSF Concentrations of CXCL13 and sCD27 Before and After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis
Neurol Neuroimmunol Neuroinflamm. (2023). DOI: 10.1212/NXI.0000000000200135
Krock E, Morado-Urbina CE, Menezes J, Hunt MA, Sandström A, Kadetoff D, Tour J, Verma V, Kultima K, Haglund L, Meloto CB, Diatchenko L, Kosek E, Svensson CI.
Fibromyalgia patients with elevated levels of anti-satellite glia cell immunoglobulin G antibodies present with more severe symptoms
Pain. (2023). DOI: 10.1097/j.pain.0000000000002881

2022

Giannisis A, Al-Grety A, Carlsson H, Patra K, Twohig D, Sando SB, Lauridsen C, Berge G, Grøntvedt GR, Bråthen G, White LR, Kultima K, Nielsen HM.
Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimers disease
Alzheimers Res Ther. (2022). DOI: 10.1186/s13195-022-01058-9
Sjölin K, Aulin J, Wallentin L, Eriksson N, Held C, Kultima K, Oldgren J, Burman J.
Serum Neurofilament Light Chain in Patients With Atrial Fibrillation
J Am Heart Assoc. (2022). DOI: 10.1161/JAHA.122.025910
Sreenivasan AP, Harrison PJ, Schaal W, Matuszewski DJ, Kultima K, Spjuth O.
Predicting protein network topology clusters from chemical structure using deep learning
J Cheminform. (2022). DOI: 10.1186/s13321-022-00622-7
Sjölin K, Kultima K, Larsson A, Freyhult E, Zjukovskaja C, Alkass K, Burman J.
Distribution of five clinically important neuroglial proteins in the human brain
Mol Brain. (2022). DOI: 10.1186/s13041-022-00935-6
Svedung Wettervik T, Folkvaljon D, Gordh T, Freyhult E, Kultima K, Ericson H, Abu Hamdeh S.
Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers
Biomedicines. (2022). DOI: 10.3390/biomedicines10050998
Snöbohm C, Malmberg F, Freyhult E, Kultima K, Fällmar D, Virhammar J.
White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery
Fluids Barriers CNS. (2022). DOI: 10.1186/s12987-022-00338-8
Carlsson H, Vaivade A, Emami Khoonsari P, Burman J, Kultima K.
Evaluation of polarity switching for untargeted lipidomics using liquid chromatography coupled to high resolution mass spectrometry
J Chromatogr B Analyt Technol Biomed Life Sci. (2022). DOI: 10.1016/j.jchromb.2022.123200
Braun M, Bjurnemark C, Seo W, Freyhult E, Nyholm D, Niemelä V, Blennow K, Zetterberg H, Fällmar D, Kultima K, Virhammar J.
Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus
Fluids Barriers CNS. (2022). DOI: 10.1186/s12987-022-00306-2
Jacquot F, Khoury S, Labrum B, Delanoe K, Pidoux L, Barbier J, Delay L, Bayle A, Aissouni Y, Barriere DA, Kultima K, Freyhult E, Hugo A, Kosek E, Ahmed AS, Jurczak A, Lingueglia E, Svensson CI, Breuil V, Ferreira T, Marchand F, Deval E.
Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Pain. (2022). DOI: 10.1097/j.pain.0000000000002596
Su J, Krock E, Barde S, Delaney A, Ribeiro J, Kato J, Agalave N, Wigerblad G, Matteo R, Sabbadini R, Josephson A, Chun J, Kultima K, Peyruchaud O, Hökfelt T, Svensson CI.
Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells
Brain Behav Immun. (2022). DOI: 10.1016/j.bbi.2022.01.003

2021

Peters K, Herman S, Khoonsari PE, Burman J, Neumann S, Kultima K.
Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid
Sci Rep. (2021). DOI: 10.1038/s41598-021-97491-1
Fellström B, Helmersson-Karlqvist J, Lind L, Soveri I, Thulin M, Ärnlöv J, Kultima K, Larsson A.
Strong Associations Between Early Tubular Damage and Urinary Cytokine, Chemokine, and Growth Factor Levels in Elderly Males and Females
J Interferon Cytokine Res. (2021). DOI: 10.1089/jir.2021.0065
Bergström S, Remnestål J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, Löwenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellgård B, Brosseron F, Heneka MT, Bosch B, Sanchez-Valle R, Månberg A, Svenningsson P, Nilsson P.
Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimers disease
Ann Clin Transl Neurol. (2021). DOI: 10.1002/acn3.51402
Boström G, Freyhult E, Virhammar J, Alcolea D, Tumani H, Otto M, Brundin RM, Kilander L, Löwenmark M, Giedraitis V, Lleó A, von Arnim CAF, Kultima K, Ingelsson M.
Different Inflammatory Signatures in Alzheimers Disease and Frontotemporal Dementia Cerebrospinal Fluid
J Alzheimers Dis. (2021). DOI: 10.3233/JAD-201565
Fellström B, Helmersson-Karlqvist J, Lind L, Soveri I, Thulin M, Ärnlöv J, Kultima K, Larsson A.
Albumin Urinary Excretion Is Associated with Increased Levels of Urinary Chemokines, Cytokines, and Growth Factors Levels in Humans
Biomolecules. (2021). DOI: 10.3390/biom11030396
Carlsson H, Rollborn N, Herman S, Freyhult E, Svenningsson A, Burman J, Kultima K.
Metabolomics of Cerebrospinal Fluid from Healthy Subjects Reveal Metabolites Associated with Ageing
Metabolites. (2021). DOI: 10.3390/metabo11020126
Zhukovsky C, Herman S, Wiberg A, Cunningham JL, Kultima K, Burman J.
Urokinase, CX3CL1, CCL2, TRAIL and IL-18 induced by interferon-β treatment
Acta Neurol Scand. (2021). DOI: 10.1111/ane.13400

2020

Ashrafian H, Sounderajah V, Glen R, Ebbels T, Blaise BJ, Kalra D, Kultima K, Spjuth O, Tenori L, Salek RM, Kale N, Haug K, Schober D, Rocca-Serra P, ODonovan C, Steinbeck C, Cano I, de Atauri P, Cascante M.
Metabolomics: The Stethoscope for the Twenty-First Century
Med Princ Pract. (2020). DOI: 10.1159/000513545
Agalave NM, Rudjito R, Farinotti AB, Khoonsari PE, Sandor K, Nomura Y, Szabo-Pardi TA, Urbina CM, Palada V, Price TJ, Erlandsson Harris H, Burton MD, Kultima K, Svensson CI.
Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity
Pain. (2020). DOI: 10.1097/j.pain.0000000000002033
Steinmetz J, Senkowski W, Lengqvist J, Rubin J, Ossipova E, Herman S, Larsson R, Jakobsson PJ, Fryknäs M, Kultima K.
Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids
ACS Omega. (2020). DOI: 10.1021/acsomega.0c01419
Remnestål J, Öijerstedt L, Ullgren A, Olofsson J, Bergström S, Kultima K, Ingelsson M, Kilander L, Uhlén M, Månberg A, Graff C, Nilsson P.
Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers
Transl Neurodegener. (2020). DOI: 10.1186/s40035-020-00198-y
Emmerich AC, Wellstein J, Ossipova E, Baumann I, Lengqvist J, Kultima K, Jakobsson PJ, Steinhilber D, Saul MJ.
Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells
Front Pharmacol. (2020). DOI: 10.3389/fphar.2020.00196
Carlsson H, Abujrais S, Herman S, Khoonsari PE, Åkerfeldt T, Svenningsson A, Burman J, Kultima K.
Targeted metabolomics of CSF in healthy individuals and patients with secondary progressive multiple sclerosis using high-resolution mass spectrometry
Metabolomics. (2020). DOI: 10.1007/s11306-020-1648-5

2019

Larsson A, Tydén J, Johansson J, Lipcsey M, Bergquist M, Kultima K, Mandic-Havelka A.
Calprotectin is superior to procalcitonin as a sepsis marker and predictor of 30-day mortality in intensive care patients
Scand J Clin Lab Invest. (2019). DOI: 10.1080/00365513.2019.1703216
Ericson H, Hamdeh SA, Freyhult E, Stiger F, Bäckryd E, Svenningsson A, Gordh T, Kultima K.
Reply to Sun et al
Pain. (2019). DOI: 10.1097/j.pain.0000000000001699
Wiberg A, Olsson-Strömberg U, Herman S, Kultima K, Burman J.
Profound but Transient Changes in the Inflammatory Milieu of the Blood During Autologous Hematopoietic Stem Cell Transplantation
Biol Blood Marrow Transplant. (2019). DOI: 10.1016/j.bbmt.2019.09.010
Ericson H, Abu Hamdeh S, Freyhult E, Stiger F, Bäckryd E, Svenningsson A, Gordh T, Kultima K.
Cerebrospinal fluid biomarkers of inflammation in trigeminal neuralgia patients operated with microvascular decompression
Pain. (2019). DOI: 10.1097/j.pain.0000000000001649
Saul MJ, Hegewald AB, Emmerich AC, Ossipova E, Vogel M, Baumann I, Kultima K, Lengqivst J, Steinhilber D, Jakobsson PJ.
Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes
Front Pharmacol. (2019). DOI: 10.3389/fphar.2019.00640
Bergqvist F, Ossipova E, Idborg H, Raouf J, Checa A, Englund K, Englund P, Khoonsari PE, Kultima K, Wheelock CE, Larsson K, Korotkova M, Jakobsson PJ.
Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells
Front Pharmacol. (2019). DOI: 10.3389/fphar.2019.00636
Abujrais S, Olovsson M, Ahnoff M, Rasmusson AJ, Larsson A, Åkerfeldt T, Kultima K.
A sensitive method detecting trace levels of levonorgestrel using LC-HRMS
Contraception. (2019). DOI: 10.1016/j.contraception.2019.06.001
Bersellini Farinotti A, Wigerblad G, Nascimento D, Bas DB, Morado Urbina C, Nandakumar KS, Sandor K, Xu B, Abdelmoaty S, Hunt MA, Ängeby Möller K, Baharpoor A, Sinclair J, Jardemark K, Lanner JT, Khmaladze I, Borm LE, Zhang L, Wermeling F, Cragg MS, Lengqvist J, Chabot-Doré AJ, Diatchenko L, Belfer I, Collin M, Kultima K, Heyman B, Jimenez-Andrade JM, Codeluppi S, Holmdahl R, Svensson CI.
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons
J Exp Med. (2019). DOI: 10.1084/jem.20181657
Idborg H, Zandian A, Ossipova E, Wigren E, Preger C, Mobarrez F, Checa A, Sohrabian A, Pucholt P, Sandling JK, Fernandes-Cerqueira C, Rönnelid J, Oke V, Grosso G, Kvarnström M, Larsson A, Wheelock CE, Syvänen AC, Rönnblom L, Kultima K, Persson H, Gräslund S, Gunnarsson I, Nilsson P, Svenungsson E, Jakobsson PJ.
Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients
Front Immunol. (2019). DOI: 10.3389/fimmu.2019.01029
Feresiadou A, Nilsson K, Ingelsson M, Press R, Kmezic I, Nygren I, Svenningsson A, Niemelä V, Gordh T, Cunningham J, Kultima K, Larsson A, Burman J.
Measurement of sCD27 in the cerebrospinal fluid identifies patients with neuroinflammatory disease
J Neuroimmunol. (2019). DOI: 10.1016/j.jneuroim.2019.03.015
Herman S, Niemelä V, Emami Khoonsari P, Sundblom J, Burman J, Landtblom AM, Spjuth O, Nyholm D, Kultima K.
Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntingtons disease subjects
Sci Rep. (2019). DOI: 10.1038/s41598-019-40186-5
Emami Khoonsari P, Moreno P, Bergmann S, Burman J, Capuccini M, Carone M, Cascante M, de Atauri P, Foguet C, Gonzalez-Beltran AN, Hankemeier T, Haug K, He S, Herman S, Johnson D, Kale N, Larsson A, Neumann S, Peters K, Pireddu L, Rocca-Serra P, Roger P, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Schober D, Selivanov V, Thévenot EA, van Vliet M, Zanetti G, Steinbeck C, Kultima K, Spjuth O.
Interoperable and scalable data analysis with microservices: applications in metabolomics
Bioinformatics. (2019). DOI: 10.1093/bioinformatics/btz160
Khoonsari PE, Shevchenko G, Herman S, Remnestål J, Giedraitis V, Brundin R, Degerman Gunnarsson M, Kilander L, Zetterberg H, Nilsson P, Lannfelt L, Ingelsson M, Kultima K.
Improved Differential Diagnosis of Alzheimers Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers
J Alzheimers Dis. (2019). DOI: 10.3233/JAD-180855

2018

Peters K, Bradbury J, Bergmann S, Capuccini M, Cascante M, de Atauri P, Ebbels TMD, Foguet C, Glen R, Gonzalez-Beltran A, Günther UL, Handakas E, Hankemeier T, Haug K, Herman S, Holub P, Izzo M, Jacob D, Johnson D, Jourdan F, Kale N, Karaman I, Khalili B, Emami Khonsari P, Kultima K, Lampa S, Larsson A, Ludwig C, Moreno P, Neumann S, Novella JA, ODonovan C, Pearce JTM, Peluso A, Piras ME, Pireddu L, Reed MAC, Rocca-Serra P, Roger P, Rosato A, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Selivanov V, Spjuth O, Schober D, Thévenot EA, Tomasoni M, van Rijswijk M, van Vliet M, Viant MR, Weber RJM, Zanetti G, Steinbeck C.
PhenoMeNal: processing and analysis of metabolomics data in the cloud
Gigascience. (2018). DOI: 10.1093/gigascience/giy149
Herman S, Khoonsari PE, Tolf A, Steinmetz J, Zetterberg H, Åkerfeldt T, Jakobsson PJ, Larsson A, Spjuth O, Burman J, Kultima K.
Integration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis
Theranostics. (2018). DOI: 10.7150/thno.26249
Novella JA, Emami Khoonsari P, Herman S, Whitenack D, Capuccini M, Burman J, Kultima K, Spjuth O.
Container-based bioinformatics with Pachyderm
Bioinformatics. (2018). DOI: 10.1093/bioinformatics/bty699
Khoonsari PE, Ossipova E, Lengqvist J, Svensson CI, Kosek E, Kadetoff D, Jakobsson PJ, Kultima K, Lampa J.
The human CSF pain proteome
J Proteomics. (2018). DOI: 10.1016/j.jprot.2018.05.012
Sandor K, Krishnan S, Agalave NM, Krock E, Salcido JV, Fernandez-Zafra T, Khoonsari PE, Svensson CI, Kultima K.
Spinal injection of newly identified cerebellin-1 and cerebellin-2 peptides induce mechanical hypersensitivity in mice
Neuropeptides. (2018). DOI: 10.1016/j.npep.2018.04.004
Khoonsari PE, Musunri S, Herman S, Svensson CI, Tanum L, Gordh T, Kultima K.
Systematic analysis of the cerebrospinal fluid proteome of fibromyalgia patients
J Proteomics. (2018). DOI: 10.1016/j.jprot.2018.04.014
Almandoz-Gil L, Welander H, Ihse E, Khoonsari PE, Musunuri S, Lendel C, Sigvardson J, Karlsson M, Ingelsson M, Kultima K, Bergström J.
Corrigendum to Low molar excess of 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote oligomerization of alpha-synuclein through different pathways [Free Rad. Biol. Med. (2017) 421-431]
Free Radic Biol Med. (2018). DOI: 10.1016/j.freeradbiomed.2018.02.007

2017

van Rijswijk M, Beirnaert C, Caron C, Cascante M, Dominguez V, Dunn WB, Ebbels TMD, Giacomoni F, Gonzalez-Beltran A, Hankemeier T, Haug K, Izquierdo-Garcia JL, Jimenez RC, Jourdan F, Kale N, Klapa MI, Kohlbacher O, Koort K, Kultima K, Le Corguillé G, Moreno P, Moschonas NK, Neumann S, ODonovan C, Reczko M, Rocca-Serra P, Rosato A, Salek RM, Sansone SA, Satagopam V, Schober D, Shimmo R, Spicer RA, Spjuth O, Thévenot EA, Viant MR, Weber RJM, Willighagen EL, Zanetti G, Steinbeck C.
The future of metabolomics in ELIXIR
F1000Res. (2017). DOI: 10.12688/f1000research.12342.2
Nikitidou E, Khoonsari PE, Shevchenko G, Ingelsson M, Kultima K, Erlandsson A.
Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-β Protofibril Exposure of Neuroglial Co-Cultures
J Alzheimers Dis. (2017). DOI: 10.3233/JAD-170278
Almandoz-Gil L, Welander H, Ihse E, Khoonsari PE, Musunuri S, Lendel C, Sigvardson J, Karlsson M, Ingelsson M, Kultima K, Bergström J.
Low molar excess of 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote oligomerization of alpha-synuclein through different pathways
Free Radic Biol Med. (2017). DOI: 10.1016/j.freeradbiomed.2017.07.004
Herman S, Emami Khoonsari P, Aftab O, Krishnan S, Strömbom E, Larsson R, Hammerling U, Spjuth O, Kultima K, Gustafsson M.
Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions
Metabolomics. (2017). DOI: 10.1007/s11306-017-1213-z

2016

Senkowski W, Jarvius M, Rubin J, Lengqvist J, Gustafsson MG, Nygren P, Kultima K, Larsson R, Fryknäs M.
Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids
Cell Chem Biol. (2016). DOI: 10.1016/j.chembiol.2016.09.013
Musunuri S, Khoonsari PE, Mikus M, Wetterhall M, Häggmark-Mänberg A, Lannfelt L, Erlandsson A, Bergquist J, Ingelsson M, Shevchenko G, Nilsson P, Kultima K.
Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic-Exocytic Proteins in the Alzheimers Disease Brain
J Alzheimers Dis. (2016). DOI: 10.3233/JAD-160271
Remnestål J, Just D, Mitsios N, Fredolini C, Mulder J, Schwenk JM, Uhlén M, Kultima K, Ingelsson M, Kilander L, Lannfelt L, Svenningsson P, Nellgård B, Zetterberg H, Blennow K, Nilsson P, Häggmark-Månberg A.
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimers disease
Proteomics Clin Appl. (2016). DOI: 10.1002/prca.201500150
Lind AL, Emami Khoonsari P, Sjödin M, Katila L, Wetterhall M, Gordh T, Kultima K.
Spinal Cord Stimulation Alters Protein Levels in the Cerebrospinal Fluid of Neuropathic Pain Patients: A Proteomic Mass Spectrometric Analysis
Neuromodulation. (2016). DOI: 10.1111/ner.12473
Khoonsari PE, Häggmark A, Lönnberg M, Mikus M, Kilander L, Lannfelt L, Bergquist J, Ingelsson M, Nilsson P, Kultima K, Shevchenko G.
Analysis of the Cerebrospinal Fluid Proteome in Alzheimers Disease
PLoS One. (2016). DOI: 10.1371/journal.pone.0150672

2015

Adori C, Barde S, Vas S, Ebner K, Su J, Svensson C, Mathé AA, Singewald N, Reinscheid RR, Uhlén M, Kultima K, Bagdy G, Hökfelt T.
Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study
Brain Struct Funct. (2015). DOI: 10.1007/s00429-015-1117-5

2014

Musunuri S, Kultima K, Richard BC, Ingelsson M, Lannfelt L, Bergquist J, Shevchenko G.
Micellar extraction possesses a new advantage for the analysis of Alzheimers disease brain proteome
Anal Bioanal Chem. (2014). DOI: 10.1007/s00216-014-8320-8
Musunuri S, Wetterhall M, Ingelsson M, Lannfelt L, Artemenko K, Bergquist J, Kultima K, Shevchenko G.
Quantification of the brain proteome in Alzheimers disease using multiplexed mass spectrometry
J Proteome Res. (2014). DOI: 10.1021/pr401202d

2013

Sjödin MO, Wetterhall M, Kultima K, Artemenko K.
Comparative study of label and label-free techniques using shotgun proteomics for relative protein quantification
J Chromatogr B Analyt Technol Biomed Life Sci. (2013). DOI: 10.1016/j.jchromb.2013.03.027
Karlsson O, Kultima K, Wadensten H, Nilsson A, Roman E, Andrén PE, Brittebo EB.
Neurotoxin-induced neuropeptide perturbations in striatum of neonatal rats
J Proteome Res. (2013). DOI: 10.1021/pr3010265

2012

Shevchenko G, Wetterhall M, Bergquist J, Höglund K, Andersson LI, Kultima K.
Longitudinal characterization of the brain proteomes for the tg2576 amyloid mouse model using shotgun based mass spectrometry
J Proteome Res. (2012). DOI: 10.1021/pr300808h

2011

2010

Scholz B, Alm H, Mattsson A, Nilsson A, Kultima K, Savitski MM, Fälth M, Sköld K, Brunström B, Andren PE, Dencker L.
Neuropeptidomic analysis of the embryonic Japanese quail diencephalon
BMC Dev Biol. (2010). DOI: 10.1186/1471-213X-10-30
Scholz B, Sköld K, Kultima K, Fernandez C, Waldemarson S, Savitski MM, Söderquist M, Borén M, Stella R, Andrén P, Zubarev R, James P.
Impact of temperature dependent sampling procedures in proteomics and peptidomics--a characterization of the liver and pancreas post mortem degradome
Mol Cell Proteomics. (2010). DOI: 10.1074/mcp.M900229-MCP200

2009

Alm H, Scholz B, Kultima K, Nilsson A, Andrén PE, Savitski MM, Bergman A, Stigson M, Fex-Svenningsen A, Dencker L.
In vitro neurotoxicity of PBDE-99: immediate and concentration-dependent effects on protein expression in cerebral cortex cells
J Proteome Res. (2009). DOI: 10.1021/pr900723c
Kultima K, Nilsson A, Scholz B, Rossbach UL, Fälth M, Andrén PE.
Development and evaluation of normalization methods for label-free relative quantification of endogenous peptides
Mol Cell Proteomics. (2009). DOI: 10.1074/mcp.M800514-MCP200
Jergil M, Kultima K, Gustafson AL, Dencker L, Stigson M.
Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects
Toxicol Sci. (2009). DOI: 10.1093/toxsci/kfp002

2008

Alm H, Kultima K, Scholz B, Nilsson A, Andrén PE, Fex-Svenningsen A, Dencker L, Stigson M.
Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex
Neurotoxicology. (2008). DOI: 10.1016/j.neuro.2008.04.021
Scholz B, Svensson M, Alm H, Sköld K, Fälth M, Kultima K, Guigoni C, Doudnikoff E, Li Q, Crossman AR, Bezard E, Andrén PE.
Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure
PLoS One. (2008). DOI: 10.1371/journal.pone.0001589

2007

Ellegren H, Hultin-Rosenberg L, Brunström B, Dencker L, Kultima K, Scholz B.
Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes
BMC Biol. (2007). DOI: 10.1186/1741-7007-5-40
Stigson M, Kultima K, Jergil M, Scholz B, Alm H, Gustafson AL, Dencker L.
Molecular targets and early response biomarkers for the prediction of developmental toxicity in vitro
Altern Lab Anim. (2007). DOI: 10.1177/026119290703500313

2006

Kultima K, Fernández EL, Scholz B, Gustafson AL, Dencker L, Stigson M.
Cadmium-induced gene expression changes in the mouse embryo, and the influence of pretreatment with zinc
Reprod Toxicol. (2006). DOI: 10.1016/j.reprotox.2006.05.007
Scholz B, Kultima K, Mattsson A, Axelsson J, Brunström B, Halldin K, Stigson M, Dencker L.
Sex-dependent gene expression in early brain development of chicken embryos
BMC Neurosci. (2006). DOI: 10.1186/1471-2202-7-12
Alm H, Scholz B, Fischer C, Kultima K, Viberg H, Eriksson P, Dencker L, Stigson M.
Proteomic evaluation of neonatal exposure to 2,2 ,4,4 ,5-pentabromodiphenyl ether
Environ Health Perspect. (2006). DOI: 10.1289/ehp.8419

2004

Kultima K, Nyström AM, Scholz B, Gustafson AL, Dencker L, Stigson M.
Valproic acid teratogenicity: a toxicogenomics approach
Environ Health Perspect. (2004). DOI: 10.1289/txg.7034

CARAMBA Research Group
Department of Medical Sciences
Uppsala University, Sweden
GitHub: github.com/caramba